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Cocaine and the teen brain: Study offers insights into addiction

When first exposed to cocaine, the adolescent brain launches a strong defensive reaction designed to minimize the drug's effects, Yale and other scientists have found. Now two new studies by a Yale...

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New tools to answer timeless questions

After finishing his PhD in molecular biophysics, Alan Jasanoff decided to veer away from that field and try looking into some of the biggest questions in neuroscience: How do we perceive things? What...

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Real-life spider men using protein found in venom to develop muscular...

While Spider-Man is capturing the imagination of theatergoers, real-life spider men in Upstate New York are working intently to save a young boy's life.

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Researchers identify potential treatment for cognitive effects of...

Columbia University Medical Center (CUMC) researchers have identified a potential medical treatment for the cognitive effects of stress-related disorders, including post-traumatic stress disorder...

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Mathematical model helps design efficient multi-drug therapies

For years, doctors treating those with HIV have recognized a relationship between how faithfully patients take the drugs they prescribe, and how likely the virus is to develop drug resistance. More...

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Scientists develop technique to decipher the dormant AIDS virus concealed in...

Scientists at the Gladstone Institutes have gotten us one step closer to understanding and overcoming one of the least-understood mechanisms of HIV infection—by devising a method to precisely track the...

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Researchers prevent heart failure in mice

(Medical Xpress)—Cardiac stress, for example a heart attack or high blood pressure, frequently leads to pathological heart growth and subsequently to heart failure. Two tiny RNA molecules play a key...

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Understanding the biomechanics of traumatic brain injury to find treatments...

Barclay Morrison, an associate professor of biomedical engineering, compares the brain's physical response to traumatic brain injury to, of all things, a gelatin dessert.

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Reasons for severe bleeding in hemophilia revealed

New insights into what causes uncontrollable bleeding in hemophilia patients are provided in a study published by Cell Press on November 20th in the Biophysical Journal. By revealing that blood clots...

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Secrets of gentle touch revealed

Stroke the soft body of a newborn fruit fly larva ever-so-gently with a freshly plucked eyelash, and it will respond to the tickle by altering its movement—an observation that has helped scientists at...

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Better understanding of the cause of Alzheimer's disease: New suggestion for...

Alzheimer's disease is the most common form of dementia, affecting over 35 million people worldwide. It is generally assumed that the clumping of beta-amyloid (Aß) protein causes neuronal loss in...

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Study of how eye cells become damaged could help prevent blindness

Light-sensing cells in the eye rely on their outer segment to convert light into neural signals that allow us to see. But because of its unique cylindrical shape, the outer segment is prone to...

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Researchers discover enzyme behind breast cancer mutations

Researchers at the University of Minnesota have uncovered a human enzyme responsible for causing DNA mutations found in the majority of breast cancers. The discovery of this enzyme – called APOBEC3B –...

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Worm offers clues to obesity

(Medical Xpress)—As obesity rates continue to rise, experts are searching for answers in the clinic and at the lab bench to determine the types and amounts of food that people should eat.

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Scientists find underlying mechanisms behind chronic inflammation-associated...

(Medical Xpress)—Inflammatory response plays a major role in both health protection and disease generation. While the symptoms of disease-related inflammatory response have been know, scientists have...

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Why a hereditary anemia is caused by genetic mutation in mechanically...

A genetic mutation that alters the kinetics of an ion channel in red blood cells has been identified as the cause behind a hereditary anemia, according to a paper published this month in the...

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Cartilage damaged from exercise may aid in early osteoarthritis detection

Osteoarthritis is the most common joint disorder, affecting about one-third of older adults, and currently there is no cure. A study published by Cell Press April 2nd in the Biophysical Journal reveals...

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In the earliest stages of arthritis, high-impact exercise may worsen...

Osteoarthritis, which affects at least 20 percent of adults in the United States, leads to deterioration of cartilage, the rubbery tissue that prevents bones from rubbing together. By studying the...

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Putting the brakes on Parkinson's: Anle138b prevents clumping of synunclein...

The earliest signs of Parkinson's disease can be deceptively mild. The first thing that movie star Michael J. Fox noticed was twitching of the little finger of his left hand. For years, he made light...

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Researchers solve 20-year puzzle of how heart regulates its beat

(Medical Xpress)—A 20-year puzzle as to how the heart regulates contraction appears to have been solved by researchers from the University of Bristol. The findings, published in the journal Biophysics,...

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